This meeting will take place at The BioPark,
The meeting chair will be Dr Steven Patterson,
If you would like to keep up to date with the agenda or book a place, please visit:www.regonline.co.uk/dendritic10
The Agenda includes:
Introduction by the Chair: Dr Steven Patterson,
Wounding the immune system with its own blade: pathogenic consequences of HIV-mediated pDC activation
Dr. Adriano Boasso,
Human immunodeficiency virus (HIV)-1 infection causes progressive impairment of the immune system in humans, characterized by depletion of CD4 T cells and loss of T cell function. Chronic activation of plasmacytoid dendritic cells (pDC) and subsequent production of type I interferon and indoleamine 2,3-dioxygenase may exert suppressive and cytotoxic effects on T cells. We manipulated HIV in order to reduce its ability to activate pDC and induce immunopathogenesis, while preserving its antigenic potential. More potent T cell memory responses were elicited against non pathogenic HIV, demonstrating that pDC activation may be deleterious rather than beneficial in this setting.
Talk title to be confirmed
Dr Siobhan Burns, Institute of Child
Talk title to be confirmed
Professor Stella Knight,
Talk title to be confirmed
Dr Andrew Stagg, Barts and The London School of Medicine and Dentistry,
Talk title to be confirmed
Diane Razanajaona-Doll,
Talk title to be confirmed
Professor Giovanna Lombardi - King's College
Human myeloid dendritic cells, different kinds, different properties
Dr Steven Patterson,
A number of distinct types of human myeloid dendritic cells (DC) have been identified. These include monocyte derived DC, Langerhans cells, dermal dendritic cells and blood myeloid (BDCA-1) dendritic cells. Much of our present knowledge of human DC biology has been gained from studies of monocyte derived DC and although this has been a highly valuable model it may not reflect the precise biological properties of different DC populations. Knowledge of the biology of these different DC types is important in the development of vaccines which may target a particular DC population. Aspects of the biology of different types of DC will be presented.
Chairman’s summing up.
The Early registration deadline is 20th July – after this time the fees double, so book early!
If you would like to keep up to date with the agenda or book a place, please visit:www.regonline.co.uk/dendritic10
|
Before the early registration deadline |
After the early registration deadline | |
|
Standard |
£249 |
£485 |
|
Academic |
£149 |
£298 |
|
Student |
£99 |
£198 |
|
IBMS |
£149 |
£298 |
The deadline for abstract submissions is 10th August.
